Fig. 11From: A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 systemThe effects of LPS or hypoxia on PPP flux in neurons. Neither LPS nor hypoxia induce the enhancement of PPP flux in neurons. Neurons were treated with Ara-C when prepared, but not with LME. Both LPS (0.01 μg/mL) (a PPP) and hypoxia (1 % O2) (b PPP) decreased PPP flux in neurons. Values are means ± SD of four flasks. **P < 0.01 versus normoxia (grouped t test). Values are mean ± SD of four flasks. *P < 0.05, **P < 0.01, ***P < 0.001 versus controls (grouped t test)Back to article page