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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 system

Fig. 8

The enhancement of PPP flux by LPS and hypoxia. LPS and hypoxia enhanced PPP flux in astroglia in an additive manner. Microglia-containing astroglia were exposed to LPS (0.01 μg/mL) for 12 h (open columns) or LPS and hypoxia for 12 h (dotted columns). Values are means ± SD of four flasks. *P < 0.05 compared with LPS(−) controls (grouped t test). # P < 0.05 compared with normoxia controls (grouped t test)

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Journal of Neuroinflammation

ISSN: 1742-2094