Skip to main content
Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Impairment of toll-like receptors 2 and 4 leads to compensatory mechanisms after sciatic nerve axotomy

Fig. 1

a Schematic drawing representing the mice paw prints under CatWalk system. Measurements used to calculate the sciatic functional index: distance between the first and fifth toes (TS- Toe spread) and third toe and hind limb pads (PL print length). b, c Cat walk analysis in crush-lesioned C3H/HePas and C3H/HeJ mice. The paw prints from each animal were obtained before and after the sciatic crush. b Graph of the sciatic functional index (SFI) values according to the group and time of evaluation. c The intensity of the paw print is shown as a percentage of the contralateral paw during 8 weeks post-surgery. The data are presented as the percentage of the pre-surgery values. d–g Ultrastructure images of the sciatic nerve from C3H/HePas and C3H/HeJ groups. d, e Contralateral and (f and g) ipsilateral stumps of sciatic nerves in wild-type and mutant mice. h Graph of the number of myelinated, unmyelinated, and degenerated fibers. Scale bar: 5 μm

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094