Fig. 5
From: Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells
Relationship between lipid bodies and endoplasmic reticulum cisternae in microglial cells at ultrastructural level following treatment with LPS, DHA, or a combination of LPS and DHA. Focal contacts between lipid vacuoles (v) and endoplasmic reticulum cisternae (er) are observed (arrowheads) under control conditions (a), as well as following treatment with LPS (b). Following treatment with DHA (c) or treatment with both LPS and DHA (d), stretches of endoplasmic reticulum cisternae are often observed in close proximity (arrowhead) with the lipid droplets (asterisks) showing a clear or a dark appearance. Long stretches of endoplasmic reticulum cisternae directly touching and surrounding the lipid droplets are particularly observed in the combined presence of LPS and DHA (d)