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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Cryopreserved vitamin D3-tolerogenic dendritic cells pulsed with autoantigens as a potential therapy for multiple sclerosis patients

Fig. 5

Reduced antigen-specific reactivity and increased percentage of regulatory T cells (Treg) of splenocytes from mice treated with frozen tolDC-MOG (f-tolDC-MOG). Percentage of CD25 + FoxP3+ cells (Treg) in ex vivo splenocytes of f-tolDC-MOG and PBS-treated mice (n = 5 and n = 6, respectively) (a). MOG-induced proliferative response from mice treated with f-tolDC-MOG (n = 5) or PBS (vehicle, n = 6). The data are expressed as stimulation index (SI). The error bars correspond to SEM. *p < 0.05, **p < 0.01 (b)

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