Fig. 1

Illustration of the distribution of the discriminant function scores for IPD, PD_LRRK2, and CON stratified by gender. While IPD patients show little overlap with PD_LRRK2 and CON indicating a good discrimination based on the immune marker profile, PD_LRRK2 and CON present a broader overlap suggesting a possibly less robust inflammation in PD_LRRK2. These findings seem similar across females and males with an overall discrimination between these three cohorts of 69.7 % for females and 72.1 % for males