Fig. 3
Peripheral inflammation up-regulates central expression of glial cell markers. mRNA fold changes (ΔmRNA) of CD11b (left panel), ionized calcium-binding adapter molecule 1 (Iba1, middle panel), and glial fibrillary acid protein (GFAP, right panel) were measured at 6 and 24 h post LPS treatment in the a hippocampus, b amygdala, and c striatum. Data represent sample means ± SEM, n = 9–11 samples/group. * = overall significance or post hoc comparison to saline treatment group. *p < 0.05–0.01; **p < 0.01–0.001; ***p < 0.001