Fig. 6
Peripheral inflammation alters expression of downstream kynurenine pathway enzymes. mRNA fold changes (ΔmRNA) of kynurenine 3-monooxygenase (KMO, left panel), kynureninase (KYNU, middle panel), and 3-hydroxyanthranilic acid dioxygenase (HAAO, right panel) were measured at 6 and 24 h following LPS injections in the (a) hippocampus, (b) amygdala, and (c) striatum. Data represent sample means ± SEM, n = 9–11 samples/group. #,* = post hoc comparison to saline treatment group. # p < 0.1–0.05; *p < 0.05–0.01; **p < 0.01–0.001; ***p < 0.001