Microglial immunophenotype in dementia with Alzheimer’s pathology

Table 7 Linear regression analyses investigating the relationship between Alzheimer’s pathology and the MMSE score in participants with and without dementia

Alzheimer’s pathology	No dementia			Dementia with Alzheimer’s pathology
Alzheimer’s pathology	β	95 % CI (β)	P	β	95 % CI (β)	P
Meningeal CAA	0.48	(−2.87; 3.82)	0.779	0.49	(−3.25; 4.24)	0.794
Parenchymal CAA	−3.63	(−9.33; 2.07)	0.210	1.67	(−3.04; 6.39)	0.482
Diffuse plaques	0.74	(−0.67; 2.15)	0.299	0.50	(−3.45; 4.45)	0.800
Neuritic plaques	0.24	(−1.61; 2.09)	0.797	−2.43	(−5.84; 0.99)	0.161
Tangles	1.83	(−3.90; 7.56)	0.528	−4.12	(−7.60; −0.65)	0.021

These analyses only included participants without dementia or with dementia with Alzheimer’s pathology. Significant negative association (italic)

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