Fig. 1

Functional outcome of mice after closed head weight-drop TBI. Outcome was assessed by using the neurological severity score (NSS), a composite score including tasks on motor function, alertness, and physiological behavior, with higher scores indicating worse deficit. Black squares indicate sham-operated mice (n = 7 on 1 h and on day 1, n = 5 on day 7), gray triangles mTBI (n = 15 1 h and on day 1, n = 9 on day 7), and open circles TBI mice (n = 10 1 h and on day 1, n = 8 on day 7), ***p < 0.001, **p < 0.01)