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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Oncostatin M promotes excitotoxicity by inhibiting glutamate uptake in astrocytes: implications in HIV-associated neurotoxicity

Fig. 5

EcoHIV induces expression and release of OSM in cultured BV2 cells. a Shows GFP (in green, showing infected cells) and DAPI (in blue, showing nuclei) staining of control and EcoHIV-infected (35,000 pg of p24, for 4 h) BV2 cells; scale bar corresponds to 25 μm. b, c Show real-time PCR analyses of HIV LTR (b) and OSM (c) mRNA in control and EcoHIV-infected (35,000 pg of p24) BV2 cells. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ### p < 0.001, n = 6. d Shows ELISA analysis of OSM proteins in culture supernatants collected from control and EcoHIV-infected (35,000 pg of p24) BV2 cells; **p < 0.01, n = 2 (in triplicates)

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Journal of Neuroinflammation

ISSN: 1742-2094