Skip to main content

Table 3 Expected sample size to obtain significant differences between the two groups using a conventional approach

From: Phenotypic clustering: a novel method for microglial morphology analysis

 

\( {\overline{m}}_{\kern0.75em \mathrm{CTRL}}\left({\overline{m}}_{\mathrm{LPS}}\right) \)

σ

n

\( {\overline{m}}_{\kern0.75em \mathrm{CTRL}}\left({\overline{m}}_{\mathrm{LPS}}\right) \)

σ

n

 

H

FC

CI

5.9 (4.9)

1.2

36

5.7 (6.1)

1.2

189

CEA (μm2)

953 (908)

253

643

950 (1184)

349

47

Cytoplasm area (μm2)

74.4 (149.4)

42.2

7

62.4 (123.0)

33.0

7

 

S

C

CI

7.9 (7.3)

1.6

114

4.5 (3.6)

0.5

7

CEA (μm2)

1378 (1499)

435

272

450 (360)

130

45

Cytoplasm area (μm2)

66.3 (129.2)

34.1

7

123.4 (177.0)

37.9

11

  1. Where \( \overline{m} \) is the mean of criteria for the control (LPS) set of data, σ is the common standard deviation of the two groups and n is the expected number of samples to obtain a significant difference