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Table 3 Expected sample size to obtain significant differences between the two groups using a conventional approach

From: Phenotypic clustering: a novel method for microglial morphology analysis

  \( {\overline{m}}_{\kern0.75em \mathrm{CTRL}}\left({\overline{m}}_{\mathrm{LPS}}\right) \) σ n \( {\overline{m}}_{\kern0.75em \mathrm{CTRL}}\left({\overline{m}}_{\mathrm{LPS}}\right) \) σ n
  H FC
CI 5.9 (4.9) 1.2 36 5.7 (6.1) 1.2 189
CEA (μm2) 953 (908) 253 643 950 (1184) 349 47
Cytoplasm area (μm2) 74.4 (149.4) 42.2 7 62.4 (123.0) 33.0 7
  S C
CI 7.9 (7.3) 1.6 114 4.5 (3.6) 0.5 7
CEA (μm2) 1378 (1499) 435 272 450 (360) 130 45
Cytoplasm area (μm2) 66.3 (129.2) 34.1 7 123.4 (177.0) 37.9 11
  1. Where \( \overline{m} \) is the mean of criteria for the control (LPS) set of data, σ is the common standard deviation of the two groups and n is the expected number of samples to obtain a significant difference
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