Fig. 6

Delayed macroglial activation in the retina after temporal SE. Representative photomicrographs of GFAP expression on macroglia in the retina of NSC (a) and 7 weeks post-SE (b). The extension of GFAP⁺ processes and their end feet in different retinal layers are visualized in (b). Arrows depict GFAP⁺ end feet of Müller cells in ILM and arrow heads mark GFAP⁺ retinal astrocytes. Quantification of GFAP⁺ Müller cell processes in the IPL showed increased expression after SE (c). Data are presented as median range with upper quartile range, n = 9 NSC and n = 6 SE group (c). *p ≤ 0.05 Mann-Whitney’s rank sum test. Scale bar is 50 μm for (a) and (b)