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Table 1 Characteristics of SOD1G93A rats used in the post-paralysis masitinib trial

From: Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis

 

Vehicle

Masitinib (>day 1)

Masitinib (>day 7)

Age at onset (days)

187 ± 15

182 ± 25

198 ± 14

Weight at onset (g)

315 ± 56

306 ± 16

323 ± 71

Weight at end-stage (g)

235 ± 13

214 ± 50

211 ± 50

Survival range (days)

174–234

177–249

201–246

  1. The table shows characteristics of the consolidated studies for rats treated with vehicle, masitinib starting 1 (>day 1) and 7 (>day 7) days after paralysis onset. Age and weight values are expressed as mean ± SD. Survival range indicates the age of rats at the time animals reached end-stage of paralysis