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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Combining systemic and stereotactic MEMRI to detect the correlation between gliosis and neuronal connective pathway at the chronic stage after stroke

Fig. 7

Microglia/macrophage activity after MCAO. Immunostaining of CD11b at the lesion core of the control (a), day 5 (b), day 7 (c), day 11 (d), and day 18 (f). The red arrow shows the round-shaped microglia/macrophages in the lesion core, and the yellow arrow shows the microglia/macrophages with extending processes adjacent to the peri-lesional area. The “photomerged” image shows the ROI of the lesion core, indicated by the box in red (f). Quantification of CD11b fluorescence intensity in the ischemic hemisphere during reperfusion (g). ** P < 0.01 versus day 7 and control. *** P < 0.001 versus day 11 and control. * P < 0.05 versus day 18 and control. * P < 0.05 versus day 7 and day 5. ** P < 0.01 versus day 11 and day 5. * P < 0.01 versus day 18 and day 11. Scale bars = 50 and 500 μm

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Journal of Neuroinflammation

ISSN: 1742-2094