Table 1 Baseline characteristics of hip fracture patients. Patients are stratified by centre and delirium status

Age, median (range)

84 (60–96)

83 (61–95)

0.18

85 (66–96)

82 (60–96)

0.02

Male (%)

19 (22)

17 (32)

0.23

19 (30)

17 (23)

0.40

IQCODE, median (IQR)^a

3.66 (3.06–4.18)

3.00 (3.00–3.27)

<0.001

3.81 (3.08–4.80)

3.03 (3.00–3.31)

<0.001

Delirium during hospital stay (%)

43 (51)^h

21 (39)

0.16

Independent in ADL (%)^b

36 (42)

49 (91)

<0.001

28 (44)

56 (77)

<0.001

Living in an institution (%)^c

30 (35)

0

<0.001

21 (33)

7 (10)

0.001

Presence of infection and/or cancer pre-operatively (%)

11 (13)

11 (20)

0.24

12 (19)

10 (13.7)

0.42

APACHE II score, median (IQR)^d

9 (7.3–10)

8 (6.8–10)

0.03

9 (8–10)

8 (7–10)

0.10

Charlson Comorbidity Index score, median (IQR)

1 (0–2)

1 (0–2)

0.66

1 (0–2)

1 (0–2)

0.06

Use of NSAIDs and/or ASA

23 (27)

23 (43)

0.06

22 (34)

24 (33)

0.85

Time from admission to surgery in hours, median (IQR)^e

28.6 (19.8–42.5)

35 (23–45.5)

0.10

36.1 (23.0–46.4)

27.4 (19.8–39.5)

0.02

Length of stay, days median (IQR)

10 (7–14)

20 (13–51)

<0.001

13 (8–21.5)

11 (8–17)

0.52

Serum neopterin, median (IQR) nmol/mL^f

28.6 (23.4–41.9)

36.1 (24.2–49.2)

0.13

37.0 (26.2–51.1)

27.1 (22.6–40.7)

0.003

CSF neopterin, median (IQR) nmol/mL^g

25.1 (20.1–37.6)

25.9 (20.8–33.0)

0.76

29.6 (22.3–40.4)

24.7 (19.4–30.6)

0.003