Table 3 Immunological correlates of AQP4-IgG binding patterns

AQP-M23 binding

4.52 (3.57–5.48)

6.02 (3.86–8.19)

0.50 (0.25–0.75)

0.999

AQP4-M1 binding

1.42 (1.01–1.83)

1.78 (0.59–2.97)

0.56 (0.33–0.78)

0.999

AQP4-M1 (% M23)

25.1 (19.3–31.1)

28.1 (10.0–31.5)

0.78 (0.59–0.97)

0.405

AQP4-mycA binding

1.95 (1.69–2.21)

5.66 (4.12–7.19)

0.99 (0.96–1.00)

<0.001

AQP4-mycA (% M23)

24.5 (18.5–30.52)

88.6 (80.4–96.8)

1.00 (1.00)

<0.001

AQP4-delA3 binding

2.15 (1.75–2.56)

5.42 (3.77–7.07)

0.96 (0.90–1.00)

<0.001

AQP4-delA3 (% M23)

28.7 (21.9–35.5)

86.2 (77.0–95.4)

0.97 (0.92–1.00)

<0.001

AQP4-mycC binding

1.36 (1.32–1.41)

1.49 (1.38–1.60)

0.88 (0.72–1.00)

0.045

AQP4-mycC (% M23)

11.1 (7.4–14.8)

20.6 (8.7–32.5)

0.72 (0.52–0. 93)

0.999

AQP4-N153Q binding

3.47 (2.86–4.07)

5.42 (3.63–7.20)

0.75 (0.58–0.92)

0.750

AQP4-N153Q (% M23)

61.3 (49.1–73.5)

89.6 (74.2–100)

0.72 (0.55–0.89)

0.999

AQP4-mycE binding

1.14 (1.11–1.17)

1.29 (1.05–1.53)

0.63 (0.33–0.92)

0.999

AQP4-mycE (% M23)

5.8 (3.7–7.9)

3.7 (2.0–5.5)

0.54 (0.36–0.71)

0.999

AQP4-H230G binding

2.35 (1.80–2.89)

3.94 (2.22–5.67)

0.71 (0.52–0.91)

0.999

AQP4-H230G (% M23)

31.3 (25.0–38.2)

53.6 (35.7–71.4)

0.74 (0.59–0.90)

0.870