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Table 2 Leads to activation of inflammatory genes by identified TFs in response to 4-h LPS stimulation in PM

From: Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia

STAT1 predicted to be activated (65 genes) (P = 1.41 E-74) STAT2 predicted to be activated (14 genes) (P = 1.03 E-41) IRF1 predicted to be activated (51 genes) (P = 4.98 E-61) IRF2 predicted to be activated (21 genes) (P = 3.55 E-35)
CASP1, CASP4, CASP8, CCL2, CCL3, CCL4, CCL5, CCRL2, CD14, CD274, CD40, CD86, CDKN1A, CLIC5, CMPK2, CSF2, CXCL10, CXCL11, CXCL2, CXCL9, FAM26F, FCER1G, GBP2, GBP3, GBP5, GBP6, ICAM1, IFI35, IFIT1, IFIT2, IFIT3, IFITM3, IFNB1, IL12B, IL15, IL15RA, IL6, IRG1, ISG15, ITGAX, JAK2, KCTD12, LCN2, MMP9, MX1, NOS2, PSMB10, PSMB9, PSMB8, PSME1, PSME2, PTGS2, RSAD2, SAMHD1, SLFN5, SOCS1, SOCS3, TAP1, TAPBPL, TNF, TNFSF10, TRAF2, TRAFD1, USP18, C3 CCL5, CXCL10, IFI35, IFIT1, IFIT2, IFIT3, IL6, ISG15, MX1, PSMB8, RSAD2, SOCS1, TNF, TNFSF10 TRIM21, TNFSF10, TNF, TLR3, TAP2, TAP1, SOCS7, SOCS1, RSAD2, PTGS2, PSMB9, PSMB10, PML, PLA2G16, PCNA, MX1, NOS2, MMP9, JAK2, ISG15, IL6, IL27, IL1B, IL18BP, IL18, IL17RA, IL15, IL12B, IFNB1, IFITM3, IFIT3, IFIT2, IFIT1, IFIH1, IFI44L, IFI35, GBP2, FPR2, EIF2AK2, CXCL16, CXCL10, CDKN1A, CD40, CD274, CCL5, CASP8, CASP7, CASP1, BRIP1, USP18, VCAM1 USP18, VCAM1, TRIM21, TNFSF10, TLR3, TAP2, TAP1, SOCS1, PTGS2, PSMB9, PSMB10, ISG15, IL6, IL1B, IL12B, IFNB1, IFI35, EIF2AK2, CXCL10, CDKN1A, CASP1