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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer’s disease

Fig. 1

Serum profiling of clinical biomarkers of neuroinflammation to predict the conversion (continuum) of MCI to AD. a The serum levels of Aβ, HMGB1, sRAGE, and s100β are shown individually for each subject belonging to age-matched control (NL), MCI, or AD cohorts to facilitate the correlation of these markers. b Serum levels of each DAMP expressed as mean (±SD) for each cohort. *p < 0.05 and ***p < 0.01. n.s. not significant

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Journal of Neuroinflammation

ISSN: 1742-2094