Fig. 1

Dynamic changes in the levels of interleukin-6 (IL-6; a), monocyte chemoattractant protein-1 (MCP-1; b), interferon-γ-inducible protein-10 (IP-10; c), and monokine induced by interferon-γ (MIG; d) in the cerebrospinal fluid of ten patients with subarachnoid hemorrhage. Data are represented as box-and-whisker plots indicating the median, the upper and lower quartiles, and the largest and the lowest values. *p < 0.05 compared with control group via one-way ANOVA, followed by Fisher’s PLSD for multiple comparisons. The correlations between the peak concentration of IL-6 and that of MCP-1 (e) and the concentrations of IP-10 and MIG on day 5 (f), according to Pearson’s correlation coefficient. The open circle represents the data from the good outcome (good recovery (GR)) patients, while the closed circle represents the data from the poor outcome (moderate disability (MD) + vegetative state (VS)) patients. Peak concentrations of IL-6 (g) in the good outcome (GR) patients and poor outcome (MD + VS) patients. *p < 0.05 by Mann-Whitney U test