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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Secreted herpes simplex virus-2 glycoprotein G alters thermal pain sensitivity by modifying NGF effects on TRPV1

Fig. 3

Injection of SgG2 blocks long-term transport of TRPV1 to the site of injection. Immunofluorescences showing the presence of TRPV1 and CGRP-positive nerves in the dermis of non-injected (a) or intradermally injected mice at 3 hpi (b) and 16 hpi (c). TRPV1 is shown in red, CGRP in green, and the cell nuclei are stained with To-Pro-3 and shown in blue. The graph represents TRPV1 quantification relative to CGRP in 10 random fields of each analyzed mouse (three mice injected). Error bars show the mean plus standard deviation. a.u. arbitrary units. ***p < 0.001

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