Fig. 4

Limb-use asymmetry test. Mean (+SEM) asymmetry score in sham-vehicle (n = 9), TBI-vehicle (n = 10), sham-EFX (n = 10), and TBI-EFX (n = 8) groups. Higher scores indicate a greater use of the unimpaired forelimb. Treatment with EFX significantly improved asymmetry score on day 2 (^## p < 0.01) and day 5 (^# p < 0.05) post-CCI compared to vehicle treatment in TBI animals. ***p < 0.001 and **p < 0.01 compared to pre-TBI; ^### p < 0.001, ^## p < 0.01, and ^# p < 0.05 compared to TBI-vehicle