Table 2 Phenotypic frequencies of HLA-DRB1 alleles in patients with MS

01:01

24 (5.5)

53 (13.5)

0.38

0.23–0.62

<0.0001

0.003

03:03

1 (0.2)

0

NA

NA

1.0000

NS

04:01

7 (1.6)

9 (2.3)

0.70

0.26–1.90

0.6151

NS

04:03

42 (9.7)

22 (5.6)

1.81

1.06–3.09

0.0276

NS

04:04

2 (0.5)

2 (0.5)

0.91

0.13–6.47

1.0000

NS

04:05

172 (39.6)

100 (25.4)

1.93

1.43–2.60

<0.0001

0.0004

04:06

42 (9.7)

26 (6.6)

1.52

0.91–2.52

0.1071

NS

04:07

2 (0.5)

4 (1.0)

0.45

0.08–2.48

0.4317

NS

04:10

24 (5.5)

8 (2.0)

2.82

1.25–6.36

0.0091

NS

07:01

1 (0.2)

2 (0.5)

0.45

0.04–5.01

0.6073

NS

07:10

1 (0.2)

0

NA

NA

1.0000

NS

08:01

1 (0.2)

1 (0.3)

0.91

0.06–14.56

1.0000

NS

08:02

38 (8.8)

29 (7.4)

1.21

0.73–2.00

0.4622

NS

08:03

63 (14.5)

56 (14.2)

1.02

0.69–1.51

0.9012

NS

09:01

72 (16.6)

104 (26.4)

0.55

0.40–0.78

0.0006

0.0198

10:01

2 (0.5)

2 (0.5)

0.91

0.13–6.47

1.0000

NS

11:01

18 (4.2)

19 (4.8)

0.85

0.44–1.65

0.6388

NS

12:01

26 (6.0)

38 (9.6)

0.60

0.36–1.00

0.0493

NS

12:02

5 (1.2)

15 (3.8)

0.29

0.11–0.82

0.0211

NS

13:01

3 (0.7)

2 (0.5)

1.36

0.23–8.21

1.0000

NS

13:02

20 (4.6)

46 (11.7)

0.37

0.21–0.63

0.0002

0.0066

13:07

0

1 (0.3)

0

NA

0.4758

NS

14:01

3 (0.7)

0

NA

NA

0.2508

NS

14:02

1 (0.2)

1 (0.3)

0.91

0.06–14.56

1.0000

NS

14:03

20 (4.6)

14 (3.6)

1.31

0.65–2.63

0.4449

NS

14:05

17 (3.9)

15 (3.8)

1.03

0.51–2.09

0.9347

NS

14:06

11 (2.5)

6 (1.5)

1.68

1.62–4.59

0.3371

NS

14:07

0

2 (0.5)

0

NA

0.2261

NS

14:54

20 (4.6)

28 (7.1)

0.63

0.35–1.14

0.1245

NS

15:01

125 (28.8)

67 (17.0)

1.97

1.41–2.76

<0.0001

0.0019

15:02

55 (12.7)

83 (21.1)

0.54

0.37–0.79

0.0012

0.0396

15:10

1 (0.2)

0

NA

NA

1.0000

NS

16:02

4 (0.9)

4 (1.0)

0.91

0.23–3.65

1.0000

NS