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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway

Fig. 2

Predicted transcription factor-binding site (TFBS) activity for gene promoters using CONFAC analysis. CONFAC compared our gene list to seven random control datasets to identify statistically over-represented TFBS in genes altered by stroke and reversed by NRG-1. CONFAC identified 12 TFBS that were statistically over-represented. Blue bars represent the average number of TFBS/promoter for each transcription factor in our data set. Red bars are the average number of TFBS/promoter for each transcription factor in the control datasets. p < 0.05 for all transcription factors in the graph

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Journal of Neuroinflammation

ISSN: 1742-2094