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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway

Fig. 6

NRG-1 reduces nuclear translocation of P65. N9 microglial cells were pre-treated with 100 ng/ml NRG-1 for 24 h followed by the absence or presence of LPS (10 μg/ml) for 3 h. Nuclear (a) and cytoplasmic (b) extracts were assayed using western blot. Nuclear extracts were assayed using ELISA (c). Data are presented from three independent experiments. Results were expressed as the mean +/− SD. Asterisk denotes significant difference compared to cells treated with only LPS (p < 0.05)

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