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Table 7 TNF-α modulated expression of TNF-α receptor genes in BMECs and SCMECs

From: Gene expression comparison reveals distinct basal expression of HOX members and differential TNF-induced response between brain- and spinal cord-derived microvascular endothelial cells

   Basal TNF-α
   BMEC vs SCMEC BMEC SCMEC
Gene Probe 12 h 24 h 48 h 12 h 24 h 48 h
Tnfrsf1a A_43_P15259 1.5 0.6 0.6 0.9 0.8 0.9 0.7
Tnfrsf1b A_43_P533794 3.1 1.3 0.6 1.1 1.4 2.8 2.3
Tnfrsf11b A_44_P458021 0.9 4.4 2.4 2.3 1.4 2.9 2.9
  1. Ratio of the values in BMECs versus SCMECs and in TNF-α treated cultures after 12, 24, and 48 h versus non-treated cultures were filtered for FC ≥1.45 (in bold) or FC ≤0.69 (in bold and in italic)
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Journal of Neuroinflammation

ISSN: 1742-2094