Fig. 2

Suppression of LPS-induced TNF-α and iNOS expression specific to synaptamide. Cells were incubated with LPS (100 ng/mL) and acylethanolamides at 10 nM. Acylethanolamides were added immediately after LPS exposure. Levels of TNF-α and iNOS (a, b; rat primary microglial cell, c, d; BV2 murine microglial cell) mRNA were determined by qPCR after 1 h incubation. The data represent the mean ± SEM at least three independent experiments. Means designated with the same letter are not significantly different