Fig. 6

T ₂-weighted MRI analysis following injection of IL13-MSC on the right and the left side of the splenium in CPZ-treated mice. a Left side: dot plot showing T ₂-relaxation times of the whole splenium of the corpus callosum (CC) in healthy control mice (n = 10), in CPZ-treated mice (CPZ control, n = 10) and in IL13-MSC grafted CPZ-treated mice (CPZ + IL13-MSC, n = 10). Right side: representative MRI image demonstrating intensity alterations in the splenium for each group (area indicated by arrows). b Left side: dot plot showing T ₂-relaxation times of the whole external capsule (EC) for each experimental group. Right side: representative MRI image demonstrating intensity alterations in the EC for each group (area indicated by the arrows). c Dot plot showing T ₂-relaxation times of the right side of the splenium for each experimental group. d Dot plot showing T ₂-relaxation times of the left side of the splenium for each experimental group. Significant differences versus the CPZ control group are indicated with three asterisks (p value ≤ 0.001). Data points indicated in red on (a, b, c and d) correspond with the MRI images provided in (a and b) and with the histological images shown in Fig. 7a and b