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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Human class I major histocompatibility complex alleles determine central nervous system injury versus repair

Fig. 3

Pathology scores of the brain. Pathologic analysis of brain areas (cerebellum, brain stem, cortex, hippocampus, striatum, corpus callosum, and meninges) at 7 days (ag) and 45 days (hn) following TMEV infection (dpi). Mouse strains shown are Aβ0.β2m0.Hβ2m+.A11+ (red open circle) and Aβ0.β2m0.Hβ2m+.B27+ (blue open square). Pathologic qualitative scores from 0 to 4 are described in the materials and methods. Each symbol represents one mouse. There were no differences between the two strains in the distribution of brain pathology at 7 days after infection (ag). At the 45-day time point, there was less brain pathology in Aβ0.β2m0.Hβ2+.B27+ mice as compared to Aβ0.β2m0.Hβ2m+.A11+mice (P = 0.027, rank sum test; hn)

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