Table 1 Standard serum and CSF parameters in HC and CIS/eRRMS

Gender (F/M)

13/4

26/14

Age at LP (years)

43.2 ± 9.2

37.8 ± 10.0

Disease duration (years)

n.a.

0.5 ± 0.9

CSF [Alb] (mg/dL)

17.0 ± 5.1

22.5 ± 9.8

Serum [Alb] (mg/dL)

4370.6 ± 379.0

4260.0 ± 333.6

Q_Alb (10⁻³)

3.9 ± 1.2

5.3 ± 2.3*

CSF [IgG] (mg/dL)

2.2 ± 0.9

3.7 ± 1.8***

Serum [IgG] (mg/dL)

1141.2 ± 215.2

1042.0 ± 197.7

Q_IgG (10⁻³)

1.9 ± 0.6

3.6 ± 1.7****

IgG Index

0.5 ± 0.1

0.7 ± 0.3***

IgG Loc (mg/dL)

0.1 ± 0.3

5.9 ± 10.2*

IgIF (%)

0 ± 0

11 ± 17*

IgGOB (%)

0%

65%****

Leukocyte counts (/μL)

2.1 ± 1.1

6.9 ± 7.7*