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Table 2 Correlation matrix between cognitive test scores with seed volume

From: Genetic effect of interleukin-1 beta (C-511T) polymorphism on the structural covariance network and white matter integrity in Alzheimer’s disease

Seed region R entorhinal L posterior cingulate R frontoinsular R dorsolateral prefrontal
MNI coordinates (25,-9,-28) (−2,-36, 35) (38, 26,-10) (44, 36, 20)
IL-1 beta genotypes C-carrier TT C-carrier TT C-carrier TT C-carrier TT
MMSE 0.189 −0.122 0.324** 0.451* 0.355** 0.464* −0.039 0.489*
CASI total scores 0.140 −0.105 0.314** 0.391* 0.286** 0.393* −0.027 0.530**
CASI EFT scores 0.109 −0.158 0.294** 0.344 0.219* 0.407* 0.000 0.510**
CASI Subdomains
 Short Term Memory 0.085 −0.012 0.308** 0.275 0.335** 0.475* 0.064 0.401*
 Orientation 0.136 −0.133 0.308** 0.376 0.342** 0.362 −0.044 0.457*
 Long Term Memory 0.188 0.074 0.172 0.351 0.148 0.131 −0.041 0.485*
 Language 0.155 −0.101 0.290** 0.394* 0.235** 0.255 −0.057 0.484*
 Drawing 0.045 −0.040 0.058 0.389* 0.054 0.281 −0.078 0.472*
 Attention −0.013 −0.174 0.200 0.376 0.246** 0.421* 0.077 0.511
 Verbal fluency 0.083 0.050 0.272** 0.406* 0.186 0.455* −0.001 0.349
 Abstract thinking 0.288** −0.298 0.174 0.291 0.200** 0.141 0.030 0.478*
 Mental manipulation −0.018 −0.028 0.285** 0.159 0.074 0.424* −0.091 0.367
  1. Numbers indicate Pearson correlation coefficients, * p < 0.05; **p < 0.01
  2. MMSE Mini-Mental State Examination, EFT executive function test, R right, L left, IL-1 interleukin-1, CASI Cognitive Abilities Screening Instrument, MNI Montreal Neurological Institute