| |
Fractional anisotropy
|
MMSE
|
CASI total scores
|
CASI EFT
|
|---|
|
Major white matter tract fractional anisotropy
|
C-carrier
|
TT
|
C-carrier
|
TT
|
C-carrier
|
TT
|
C-carrier
|
TT
|
|---|
|
Forceps major
|
0.47(0.04)
|
0.48(0.05)
|
0.25*
|
0.40*
|
0.29**
|
0.34
|
0.35**
|
0.40*
|
|
Forceps minor
|
0.35(0.03)
|
0.35(0.03)
|
0.26*
|
0.48*
|
0.28**
|
0.44*
|
0.34**
|
0.52*
|
|
Anterior thalamic radiation
|
0.60(0.06)
|
0.61(0.06)
|
0.22*
|
0.48*
|
0.24*
|
0.42*
|
0.30**
|
0.48*
|
|
Corticospinal tract
|
0.99(0.06)
|
0.99(0.06)
|
0.37**
|
0.10
|
0.39**
|
0.07
|
0.44**
|
0.17
|
|
Cingulum
|
0.68(0.06)
|
0.68(0.07)
|
0.29**
|
0.41*
|
0.32**
|
0.36
|
0.32**
|
0.43*
|
|
Cingulum (hippocampus)
|
0.58(0.07)
|
0.59(0.06)
|
0.41**
|
0.18
|
0.45**
|
0.16
|
0.38**
|
0.17
|
|
Inferior fronto-occipital fasciculus
|
0.74(0.05)
|
0.74(0.06)
|
0.22*
|
0.29
|
0.26*
|
0.24
|
0.34**
|
0.29
|
|
Inferior longitudinal fasciculus
|
0.74(0.05)
|
0.75(0.05)
|
0.26*
|
0.31
|
0.30**
|
0.29
|
0.37**
|
0.32
|
|
Superior longitudinal fasciculus
|
0.63(0.05)
|
0.63(0.06)
|
0.20*
|
0.24
|
0.23*
|
0.22
|
0.27**
|
0.29
|
|
Uncinate fasciculus
|
0.68(0.05)
|
0.68(0.04)
|
0.26*
|
0.20
|
0.28**
|
0.13
|
0.30**
|
0.17
|
|
Superior longitudinal fasciculus (temporal part)
|
0.90(0.08)
|
0.89(0.09)
|
0.14
|
0.26
|
0.18
|
0.27
|
0.24*
|
0.32
|
- Data of Fractional Anisotropy represent mean (standard deviation), MMSE Mini-Mental State Examination scores, CASI Cognitive Ability Screening Instrument, EFT executive function test, EFT Sum of attention, verbal fluency, abstract thinking, and mental manipulation sub-domain scores of the CASI, TT T homozygotes
- Numbers indicate mean and standard deviation or Pearson correlation coefficient; *p < 0.05 **p < 0.01
