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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Microglia-derived IL-1β contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats

Fig. 1

LPS inhibits axon development. a–j show NFL, NFM, and NFH protein expression in the PWM of postnatal rats at 7, 14, and 28 days after LPS injection and their corresponding controls. Immunofluorescene shows NFL expression in PWM of postnatal rats at 7, 14, and 28 days after LPS injection (b, d, and f) and their corresponding controls (a, c, and e). g The immunoactive bands of NFL (68 kDa), NFM (160 kDa), NFH (200 kDa), and β-actin (42 kDa) by western blot analysis. h–j Bar graphs depicting significant decrease in the optical density of NFL, NFM, and NFH expression, respectively, following LPS challenge when compared with matched control. *P < 0.05, **P < 0.01. Scale bars: a–f 100 μm

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Journal of Neuroinflammation

ISSN: 1742-2094