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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Combined effect of BCG vaccination and enriched environment promote neurogenesis and spatial cognition via a shift in meningeal macrophage M2 polarization

Fig. 3

BCG vaccination induced hippocampal long-term potentiation induced by high-frequency stimulation (HFS) 20 min after baseline recordings in the DG in vivo. LTP is expressed as percentage potentiation of baseline (100%), and the significance is determined at 58–60 min after the HFS was given. a Traces (top) represent a typical response before (red line) and after (blue line) HFS. b BCG vaccination induces higher LTP both in mice raised both in regular environment and an enriched environment. c Potentiation of fEPSP at 58–60 min after HFS. Data in c are presented as the means ± SEMs (*p < 0.05; two-way ANOVA, LSD post hoc test, n = 6–8 per group)

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