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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Fingolimod additionally acts as immunomodulator focused on the innate immune system beyond its prominent effects on lymphocyte recirculation

Fig. 4

Phagocytosis and apoptosis after FTY. a SlanDCs (A), CD1 + DCs (B), and monocytes (C) were treated with different concentrations of FTY or FTYP before phagocytosis of carboxylate-modified yellow–green fluorescent beads was evaluated. Mean values ± SEM of eight individual experiments are presented. Bonferroni’s correction was used. Asterisks indicate a statistically significant difference (*p < 0.05, **p < 0.01). b SlanDCs (A), CD1+ DCs (B), and monocytes (C) were treated with different concentrations of FTY or FTYP for 24 h (A–C) or 48 h (data not shown). Afterwards, apoptosis at early (gray bar) and late stage (white bar) was evaluated. Mean values ± SEM of eight individual experiments are presented

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