Table 1 Demographic and clinical characteristics of nAMD patients and controls from secreted cytokines analysis (experiment 2)

Age (median (range)), years

77.2 (57–93)

74.5 (59–92)

78.1 (57–93)

0.066^a

Female sex (number (%))

58 (56)

14 (50)

44 (59)

0.505^b

Family history of AMD (number (%))

25 (24)

4 (14)

21 (28)

0.202^b

Cardiovascular disease (number (%))

27 (26)

6 (21)

21 (28)

0.621^b

Hypertension (number (%))

62 (60)

12 (43)

50 (67)

0.065^b

Diabetes (number (%))

12 (12)

1 (4)

11 (15)

0.175^b

Body mass index (mean ± SD)

25.8 (4.0)

25.2 (3.8)

26.1 (4.0)

0.318^c

Smoking status

0.883^b

 Non-smoker (number (%))

40 (39)

12 (43)

28 (37)

 Former smoker (number (%))

54 (52)

13 (46)

41 (55)

 Current smoker (number (%))

8 (8)

2 (7)

6 (8)

Taking medication for CVD (number (%))

73 (71)

17 (61)

56 (75)

0.320^b

Vitamin supplementation (number (%))

21 (20)

2 (7)

19 (25)

0.055^b

Taking low-dose aspirin (number (%))

33 (32)

3 (11)

30 (40)

0.008 ^b