Fig. 3

Median serum interleukin (IL)-1β, IL-4, IL-6, IL-8, IL-10 and TNF-α concentrations. Serum cytokine levels from both HT (blue) and NT (red) groups were assessed over time from baseline until termination (48 h). TNF-α levels were clearly decreased in the HT group between baseline and 12 h readouts, when compared to NT, *p < 0.05. The shaded areas represent the hypothermia (24 h, blue) and rewarming (10 h, orange) phases