Skip to main content

Table 4 Correlation of piglet neonatal CSF cytokine levels at 48 h after hypoxia-ischemia with cerebral metabolite ratios assessed by proton-MRS

From: Systemic pro-inflammatory cytokine status following therapeutic hypothermia in a piglet hypoxia-ischemia model

Cytokines

Lac/NAA

NAA/Cr

Lac/Cr

Basal ganglia

White matter

Basal ganglia

White matter

Basal ganglia

White matter

Coef

p Value

Coef

p Value

Coef

p Value

Coef

p Value

Coef

p Value

Coef

p Value

IL-1β

0.59

0.13

0.49

0.22

−0.66

0.08

−0.50

0.20

0.59

0.13

0.49

0.22

IL-4

−0.06

0.88

0.09

0.83

0.17

0.67

−0.03

0.95

−0.06

0.88

0.09

0.83

IL-6

0.28

0.51

0.16

0.71

−0.16

0.71

−0.07

0.87

0.28

0.51

0.19

0.65

IL-8

−0.10

0.82

0.02

0.95

−0.05

0.91

0.10

0.82

−0.10

0.82

0.15

0.73

IL-10

0.15

0.73

0.16

0.70

−0.01

0.89

0.02

0.95

0.15

0.73

0.16

0.71

TNF-α

0.60

0.12

0.80

0.02

−0.89

0.003

−0.87

0.005

0.60

0.12

0.80

0.02

  1. Bold p values indicate significance at p < 0.05
  2. Statistical association based on Spearman’s rank correlation