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Table 4 Correlation of piglet neonatal CSF cytokine levels at 48 h after hypoxia-ischemia with cerebral metabolite ratios assessed by proton-MRS

From: Systemic pro-inflammatory cytokine status following therapeutic hypothermia in a piglet hypoxia-ischemia model

Cytokines Lac/NAA NAA/Cr Lac/Cr
Basal ganglia White matter Basal ganglia White matter Basal ganglia White matter
Coef p Value Coef p Value Coef p Value Coef p Value Coef p Value Coef p Value
IL-1β 0.59 0.13 0.49 0.22 −0.66 0.08 −0.50 0.20 0.59 0.13 0.49 0.22
IL-4 −0.06 0.88 0.09 0.83 0.17 0.67 −0.03 0.95 −0.06 0.88 0.09 0.83
IL-6 0.28 0.51 0.16 0.71 −0.16 0.71 −0.07 0.87 0.28 0.51 0.19 0.65
IL-8 −0.10 0.82 0.02 0.95 −0.05 0.91 0.10 0.82 −0.10 0.82 0.15 0.73
IL-10 0.15 0.73 0.16 0.70 −0.01 0.89 0.02 0.95 0.15 0.73 0.16 0.71
TNF-α 0.60 0.12 0.80 0.02 −0.89 0.003 −0.87 0.005 0.60 0.12 0.80 0.02
  1. Bold p values indicate significance at p < 0.05
  2. Statistical association based on Spearman’s rank correlation