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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Early strong intrathecal inflammation in cerebellar type multiple system atrophy by cerebrospinal fluid cytokine/chemokine profiles: a case control study

Fig. 3

Correlations between disease durations and cytokine levels in MSA-C patients. a Heatmap analysis of correlations between cytokine levels and disease duration. R values of Pearson’s correlation coefficient analysis are divided into quintiles, and p values calculated using one-way ANOVA are indicated as a heatmap. Note the significant negative correlation between MCP-1 and disease duration (R = −0.57, p = 0.0088). b Linear regression analysis shows a strong negative correlation between CSF MCP-1 and disease duration in MSA-C. Mean value ± 2 SD observed in OND patients is indicated as a gray bar (mean ± 2 SD = 378.1 ± 214.4 pg/μL). CSF: cerebrospinal fluid, MCP-1: macrophage chemoattractant protein-1, MSA-C: multiple system atrophy cerebellar-type, OND: other non-inflammatory neurological diseases

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