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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Early strong intrathecal inflammation in cerebellar type multiple system atrophy by cerebrospinal fluid cytokine/chemokine profiles: a case control study

Fig. 6

Correlations between CSF cytokine levels and HCBS scores in MSA-C patients. a Classification of HCBS. Grade 1, faint hyper-intense anteroposterior line compared with horizontal line; Grade 2, definite HCBS on a single slice; Grade 3, prominent HCBS on two or more sequential slices. b Heatmap of the p-values of one-way ANOVA analysis. Only the IL-6 level significantly correlated with HCBS score (p = 0.0453). c Comparison of CSF IL-6 levels with HCBS scores. The CSF IL-6 level was significantly lower in patients with higher HCBS scores using the Fisher’s PLSD multiple comparison test (p = 0.0142). *p < 0.05. CSF: cerebrospinal fluid, HCBS: hot cross bun sign, IL: interleukin, MSA-C: multiple system atrophy cerebellar-type, PLSD: protected least significant differentiation

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Journal of Neuroinflammation

ISSN: 1742-2094