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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage

Fig. 1

Endovascular perforation model of SAH and experimental design. a SAH severity levels; rats with a score below 5 points were excluded due to low SAH grade. b–e Experimental design of this study. SD rats Sprague–Dawley rats, SAH subarachnoid haemorrhage, TXNIP thioredoxin-interacting protein, RES resveratrol, siRNA small interfering RNA, BBB blood–brain barrier, TUNEL terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labelling, PERK protein kinase RNA-like ER kinase, IRE1α inositol-requiring enzyme-1α, DMSO dimethylsulfoxide

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