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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface

Fig. 3

Comparison of ChP cytokine-responsive genes (GO:0034097) after LPS challenge between genotypes. Expression levels were investigated by transcriptome analysis (Illumina HiSeq 2000) on RNA extracted from the choroid plexus. Transcripts of genes stimulated primarily by type I interferons increased in PrPC-deficient goats compared with PRNP +/+ goats, whereas genes stimulated primarily by type II interferons were reduced. *Fold change ±1.2 and p < 0.05. n = 15

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