Fig. 1
From: Adaptive lymphocyte profiles correlate to brain Aβ burden in patients with mild cognitive impairment
PET reflects dysregulation of Aβ clearance. a, b Representative PET images and values corresponding to the standardized uptake value ratio (SUVR), with image of the posterior cingulate cortex (PCC). c Increases in PCC SUVR predict total amyloid burden (mean cortex). d PCC SUVR increase corresponds to a decrease in soluble CSF Aβ42. e, f Increases in precuneous cortex SUVR also predict total amyloid burden, but without the significant decrease in soluble CSF Aβ42. Linear regression (solid lines) and 95% confidence interval (dotted lines) shown. *p < 0.05, ***p < 0.001