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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Chronic glucocorticoid exposure activates BK-NLRP1 signal involving in hippocampal neuron damage

Fig. 9

Effect of DEX and IbTx treatment on the BK currents in hippocampal neurons (whole-cell patch-clamp technology). a Representative traces of potassium currents induced by BK channel inhibitor IbTx. b Representative traces of potassium currents induced by DEX. c Representative traces of potassium currents induced by DEX and IbTx. d Statistical results showing recorded potassium currents were markedly inhibited by specific BK channel inhibitor IbTx. e Statistical results showing DEX increased BK currents. f Statistical results showing DEX failed to increase BK currents in the presence of IbTx. Results are expressed as mean ± SD, n = 5 or n = 4. # P < 0.05, ## P < 0.01 compared to control group; **P < 0.01compared to DEX- or IbTx-treated group

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