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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Ischaemic stroke and the recanalization drug tissue plasminogen activator interfere with antibacterial phagocyte function

Fig. 3

Influence of r-tPA on phagocytosis. PBMCs of healthy donors were incubated with 0.5 or 1 μg/ml r-tPA for 4 h at 37 °C in 5% CO2. Phagocytosis was then induced using FITC-labelled opsonized E. coli. The percentage of phagocytosing cells (a, b) and the efficacy of phagocytosis defined as the MFI (c, d) were investigated for granulocytes (a, c) and monocytes (b, d) (n = 10). *p < 0.01; ***p < 0.005. The mean and SD ranges are given. Repeated measures ANOVA and Bonferroni comparisons as post hoc tests were used

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