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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury

Fig. 4

Effect of FTY720 treatment on the number of NG2+ cells at the level of the dorsal hippocampus. a Schematic diagram of measured areas in the ipsilateral hemisphere (dorsal hippocampus level), in hilus (H), fimbria (F) and corpus callosum (CC). b Representative Z-stack maximal projection of immufluorescence staining for BrdU and NG2 in the (i) hilus, (ii) fimbria and (iii) corpus callosum (KA + FTY720 group). Scale bar: 50 μm. cj Quantitative analysis of BrdU+ and NG2+/BrdU+ cells. NG2 and BrdU colocalization was determined examining three-dimensional orthogonal reconstruction of confocal layers (ImageJ software). Data are presented as cf mean of positive cells per mm2 ± SEM and gj percentage of NG2+ cells over BrdU+ total cells per mm2. Statistical analysis: unpaired, two-tailed Student t test; *p < 0.05, **p < 0.01. N = 4 animals for each experimental group

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