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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental Streptococcus pneumoniae meningitis

Fig. 9

BDNF activates the PI3K/AKT-signaling pathway in brain tissue 24 h post-infection with PM. Levels of phosphorylated PI3K and AKT in the a, b, e, f hippocampus and c, d, g, h cortex as examined by western blot using specific antibodies. BDNF administration increased levels of phosphorylated PI3K and AKT, whereas k252a pretreatment decreased these levels. **p < 0.01

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Journal of Neuroinflammation

ISSN: 1742-2094