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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Arginine vasopressin altered the expression of monocarboxylate transporters in cultured astrocytes isolated from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats

Fig. 5

Effect of AVP on expression of MCT4 protein in astrocytes isolated from WKY/Izm, SHRSP/Izm, and SHRpch1_18 rats. Astrocytes isolated from WKY/Izm, SHRSP/Izm, and SHRpch1_18 rats were exposed to 0 or 100 nM AVP for 24 h, after which MCT4 protein was assessed by WB analysis (a). In addition, astrocytes isolated from WKY/Izm were treated with or without AVP (100 nM), AVP plus CPTIO and SNP for 24 h (b). Astrocytes were exposed to CPTIO (200 μM) for 60 min before addition of AVP and 20 μM SNP. Total protein (30 μg) was analyzed by Western blot with an anti-MCT1 antibody or an anti-MCT4 antibody. AVP arginine vasopressin, WKY WKY/Izm, SHRSP SHRSP/Izm, SHRpch SHRpch1_18, AVP arginine vasopressin, SNP sodium nitroprusside. Columns show means ± SE (n = 4). *P < 0.05

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Journal of Neuroinflammation

ISSN: 1742-2094