Fig. 3

Caspase-1 activation contributes to early brain injury after SAH. a Representative western blots and densitometric analyses showing levels of IL-1ß. The bar represents the mean ± SD. **P < 0.01 vs sham. ^## P < 0.01 vs vehicle control. b Representative western blots and densitometric analyses showing levels of IL-18 (n = 6/group). The bar represents the mean ± SD. **P < 0.01 vs sham. ^## P < 0.01 vs vehicle control. c Representative photomicrographs of PI staining of neural cells in different groups at 24 h after SAH (n = 3/group). Fluorescence colors: DAPI: blue and PI: red. Scale bar = 100 μm. d The quantification of the PI-positive neural cells. The quantification of the PI-positive neural cells expressed as positive cells per square millimeter. The bar represents the mean±SD. **P < 0.01 vs sham, ^## P < 0.01 vs vehicle control. e Quantification of neurological scores (n = 9). The bars represent the mean with interquartile range. *P < 0.05 vs sham. ^# P < 0.05 vs vehicle control. f Quantification of SAH severity (n = 9). The bars represent the mean ± SD. No significant difference was observed between vehicle and SAH+AC-YVAD-CMK group