Fig. 8

ASH modulated NF-κB signaling pathway in the hypothalamus. a, b Representative Western blot analysis for markers of NF-κB pathway in the hypothalamus region of the brain among the LFD, HFD, and HFDE animals. Histograms represent percent change in intensity taking value in LFD rats as 100%. c Histograms representing fold change in mRNA expression of NF-κB and Bcl-xL in the hypothalamus region of rat brain among the four groups of animals (n = 3–4 each group). Values are expressed as mean ± SEM. * p ≤ 0.05 LFD versus HFD, LFDE, and HFDE rats, ^# p ≤ 0.05 HFD versus HFDE rats, ^$ p ≤ 0.05 HFD versus LFDE rats, ^@ p ≤ 0.05 LFDE versus HFDE rats, Holm–Sidak method after one-way ANOVA